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Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age

(1) Background: Massive social efforts to prevent the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have affected the epidemiological features of respiratory infections. (2) Methods: The study aims to describe the trend of hospitalizations for bronchiolitis amon...

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Autores principales: De Rose, Domenico Umberto, Caoci, Stefano, Auriti, Cinzia, Maddaloni, Chiara, Capolupo, Irma, Salvatori, Guglielmo, Brusco, Carla, Coltella, Luana, Concato, Carlo, Russo, Cristina, Colagrossi, Luna, Perno, Carlo Federico, Braguglia, Annabella, Villani, Alberto, Dotta, Andrea, Raponi, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611509/
https://www.ncbi.nlm.nih.gov/pubmed/36297143
http://dx.doi.org/10.3390/pathogens11101086
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author De Rose, Domenico Umberto
Caoci, Stefano
Auriti, Cinzia
Maddaloni, Chiara
Capolupo, Irma
Salvatori, Guglielmo
Brusco, Carla
Coltella, Luana
Concato, Carlo
Russo, Cristina
Colagrossi, Luna
Perno, Carlo Federico
Braguglia, Annabella
Villani, Alberto
Dotta, Andrea
Raponi, Massimiliano
author_facet De Rose, Domenico Umberto
Caoci, Stefano
Auriti, Cinzia
Maddaloni, Chiara
Capolupo, Irma
Salvatori, Guglielmo
Brusco, Carla
Coltella, Luana
Concato, Carlo
Russo, Cristina
Colagrossi, Luna
Perno, Carlo Federico
Braguglia, Annabella
Villani, Alberto
Dotta, Andrea
Raponi, Massimiliano
author_sort De Rose, Domenico Umberto
collection PubMed
description (1) Background: Massive social efforts to prevent the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have affected the epidemiological features of respiratory infections. (2) Methods: The study aims to describe the trend of hospitalizations for bronchiolitis among newborns and infants up to three months of life in Rome (Italy), in the pre-COVID-19 era and during the pandemic. (3) Results: We observed a marked decrease in the number of neonates and infants with bronchiolitis after national lockdowns in 2020 and the first months of 2021 and a similar trend in the number of bronchiolitis caused by respiratory syncytial virus (RSV). RSV was the leading pathogen responsible for bronchiolitis before the national lockdown in March 2020 (70.0% of cases), while Rhinovirus was the leading pathogen responsible for bronchiolitis (62.5%) during the pandemic while strict restrictions were ongoing. As Italy approached the COVID-19 vaccination target, the national government lifted some COVID-19-related restrictions. A surprising rebound of bronchiolitis (particularly cases caused by RSV) was observed in October 2021. (4) Conclusions: In this study, we describe for the first time the fluctuations over time of RSV bronchiolitis among newborns and young infants in Italy in relation to the restrictive measures containing the spread of the COVID-19 pandemic. Our results are in line with other countries’ reports.
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spelling pubmed-96115092022-10-28 Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age De Rose, Domenico Umberto Caoci, Stefano Auriti, Cinzia Maddaloni, Chiara Capolupo, Irma Salvatori, Guglielmo Brusco, Carla Coltella, Luana Concato, Carlo Russo, Cristina Colagrossi, Luna Perno, Carlo Federico Braguglia, Annabella Villani, Alberto Dotta, Andrea Raponi, Massimiliano Pathogens Brief Report (1) Background: Massive social efforts to prevent the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have affected the epidemiological features of respiratory infections. (2) Methods: The study aims to describe the trend of hospitalizations for bronchiolitis among newborns and infants up to three months of life in Rome (Italy), in the pre-COVID-19 era and during the pandemic. (3) Results: We observed a marked decrease in the number of neonates and infants with bronchiolitis after national lockdowns in 2020 and the first months of 2021 and a similar trend in the number of bronchiolitis caused by respiratory syncytial virus (RSV). RSV was the leading pathogen responsible for bronchiolitis before the national lockdown in March 2020 (70.0% of cases), while Rhinovirus was the leading pathogen responsible for bronchiolitis (62.5%) during the pandemic while strict restrictions were ongoing. As Italy approached the COVID-19 vaccination target, the national government lifted some COVID-19-related restrictions. A surprising rebound of bronchiolitis (particularly cases caused by RSV) was observed in October 2021. (4) Conclusions: In this study, we describe for the first time the fluctuations over time of RSV bronchiolitis among newborns and young infants in Italy in relation to the restrictive measures containing the spread of the COVID-19 pandemic. Our results are in line with other countries’ reports. MDPI 2022-09-23 /pmc/articles/PMC9611509/ /pubmed/36297143 http://dx.doi.org/10.3390/pathogens11101086 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
De Rose, Domenico Umberto
Caoci, Stefano
Auriti, Cinzia
Maddaloni, Chiara
Capolupo, Irma
Salvatori, Guglielmo
Brusco, Carla
Coltella, Luana
Concato, Carlo
Russo, Cristina
Colagrossi, Luna
Perno, Carlo Federico
Braguglia, Annabella
Villani, Alberto
Dotta, Andrea
Raponi, Massimiliano
Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title_full Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title_fullStr Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title_full_unstemmed Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title_short Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age
title_sort lessons from sars-cov-2 pandemics: how restrictive measures impacted the trend of respiratory infections in neonates and infants up to three months of age
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611509/
https://www.ncbi.nlm.nih.gov/pubmed/36297143
http://dx.doi.org/10.3390/pathogens11101086
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