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DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network

Alzheimer’s Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model’s prediction...

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Autores principales: Ahmed, Gulnaz, Er, Meng Joo, Fareed, Mian Muhammad Sadiq, Zikria, Shahid, Mahmood, Saqib, He, Jiao, Asad, Muhammad, Jilani, Syeda Fizzah, Aslam, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611525/
https://www.ncbi.nlm.nih.gov/pubmed/36296677
http://dx.doi.org/10.3390/molecules27207085
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author Ahmed, Gulnaz
Er, Meng Joo
Fareed, Mian Muhammad Sadiq
Zikria, Shahid
Mahmood, Saqib
He, Jiao
Asad, Muhammad
Jilani, Syeda Fizzah
Aslam, Muhammad
author_facet Ahmed, Gulnaz
Er, Meng Joo
Fareed, Mian Muhammad Sadiq
Zikria, Shahid
Mahmood, Saqib
He, Jiao
Asad, Muhammad
Jilani, Syeda Fizzah
Aslam, Muhammad
author_sort Ahmed, Gulnaz
collection PubMed
description Alzheimer’s Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model’s prediction accuracy depends on the dataset’s size. The DL models lose their accuracy when the dataset has an imbalanced class problem. This study aims to use the deep Convolutional Neural Network (CNN) to develop a reliable and efficient method for identifying Alzheimer’s disease using MRI. In this study, we offer a new CNN architecture for diagnosing Alzheimer’s disease with a modest number of parameters, making it perfect for training a smaller dataset. This proposed model correctly separates the early stages of Alzheimer’s disease and displays class activation patterns on the brain as a heat map. The proposed Detection of Alzheimer’s Disease Network (DAD-Net) is developed from scratch to correctly classify the phases of Alzheimer’s disease while reducing parameters and computation costs. The Kaggle MRI image dataset has a severe problem with class imbalance. Therefore, we used a synthetic oversampling technique to distribute the image throughout the classes and avoid the problem. Precision, recall, F1-score, Area Under the Curve (AUC), and loss are all used to compare the proposed DAD-Net against DEMENET and CNN Model. For accuracy, AUC, F1-score, precision, and recall, the DAD-Net achieved the following values for evaluation metrics: 99.22%, 99.91%, 99.19%, 99.30%, and 99.14%, respectively. The presented DAD-Net outperforms other state-of-the-art models in all evaluation metrics, according to the simulation results.
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spelling pubmed-96115252022-10-28 DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network Ahmed, Gulnaz Er, Meng Joo Fareed, Mian Muhammad Sadiq Zikria, Shahid Mahmood, Saqib He, Jiao Asad, Muhammad Jilani, Syeda Fizzah Aslam, Muhammad Molecules Article Alzheimer’s Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model’s prediction accuracy depends on the dataset’s size. The DL models lose their accuracy when the dataset has an imbalanced class problem. This study aims to use the deep Convolutional Neural Network (CNN) to develop a reliable and efficient method for identifying Alzheimer’s disease using MRI. In this study, we offer a new CNN architecture for diagnosing Alzheimer’s disease with a modest number of parameters, making it perfect for training a smaller dataset. This proposed model correctly separates the early stages of Alzheimer’s disease and displays class activation patterns on the brain as a heat map. The proposed Detection of Alzheimer’s Disease Network (DAD-Net) is developed from scratch to correctly classify the phases of Alzheimer’s disease while reducing parameters and computation costs. The Kaggle MRI image dataset has a severe problem with class imbalance. Therefore, we used a synthetic oversampling technique to distribute the image throughout the classes and avoid the problem. Precision, recall, F1-score, Area Under the Curve (AUC), and loss are all used to compare the proposed DAD-Net against DEMENET and CNN Model. For accuracy, AUC, F1-score, precision, and recall, the DAD-Net achieved the following values for evaluation metrics: 99.22%, 99.91%, 99.19%, 99.30%, and 99.14%, respectively. The presented DAD-Net outperforms other state-of-the-art models in all evaluation metrics, according to the simulation results. MDPI 2022-10-20 /pmc/articles/PMC9611525/ /pubmed/36296677 http://dx.doi.org/10.3390/molecules27207085 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ahmed, Gulnaz
Er, Meng Joo
Fareed, Mian Muhammad Sadiq
Zikria, Shahid
Mahmood, Saqib
He, Jiao
Asad, Muhammad
Jilani, Syeda Fizzah
Aslam, Muhammad
DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title_full DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title_fullStr DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title_full_unstemmed DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title_short DAD-Net: Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
title_sort dad-net: classification of alzheimer’s disease using adasyn oversampling technique and optimized neural network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611525/
https://www.ncbi.nlm.nih.gov/pubmed/36296677
http://dx.doi.org/10.3390/molecules27207085
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