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PEGylation of the antimicrobial peptide LyeTx I-b maintains structure-related biological properties and improves selectivity

The biological activity of antimicrobial peptides and proteins is closely related to their structural aspects and is sensitive to certain post-translational modifications such as glycosylation, lipidation and PEGylation. However, PEGylation of protein and peptide drugs has expanded in recent years d...

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Detalles Bibliográficos
Autores principales: Moreira Brito, Júlio César, Carvalho, Lucas Raposo, Neves de Souza, Amanda, Carneiro, Guilherme, Magalhães, Paula Prazeres, Farias, Luiz Macêdo, Guimarães, Natália Rocha, Verly, Rodrigo Moreira, Resende, Jarbas Magalhães, Elena de Lima, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611540/
https://www.ncbi.nlm.nih.gov/pubmed/36310605
http://dx.doi.org/10.3389/fmolb.2022.1001508