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PEGylation of the antimicrobial peptide LyeTx I-b maintains structure-related biological properties and improves selectivity
The biological activity of antimicrobial peptides and proteins is closely related to their structural aspects and is sensitive to certain post-translational modifications such as glycosylation, lipidation and PEGylation. However, PEGylation of protein and peptide drugs has expanded in recent years d...
Autores principales: | Moreira Brito, Júlio César, Carvalho, Lucas Raposo, Neves de Souza, Amanda, Carneiro, Guilherme, Magalhães, Paula Prazeres, Farias, Luiz Macêdo, Guimarães, Natália Rocha, Verly, Rodrigo Moreira, Resende, Jarbas Magalhães, Elena de Lima, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611540/ https://www.ncbi.nlm.nih.gov/pubmed/36310605 http://dx.doi.org/10.3389/fmolb.2022.1001508 |
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