TDP-43 CSF Concentrations Increase Exponentially with Age in Metropolitan Mexico City Young Urbanites Highly Exposed to PM(2.5) and Ultrafine Particles and Historically Showing Alzheimer and Parkinson’s Hallmarks. Brain TDP-43 Pathology in MMC Residents Is Associated with High Cisternal CSF TDP-43 Concentrations

Environmental exposures to fine particulate matter (PM(2.5)) and ultrafine particle matter (UFPM) are associated with overlapping Alzheimer’s, Parkinson’s and TAR DNA-binding protein 43 (TDP-43) hallmark protein pathologies in young Metropolitan Mexico City (MMC) urbanites. We measured CSF concentra...

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Detalles Bibliográficos
Autores principales: Calderón-Garcidueñas, Lilian, Stommel, Elijah W., Lachmann, Ingolf, Waniek, Katharina, Chao, Chih-Kai, González-Maciel, Angélica, García-Rojas, Edgar, Torres-Jardón, Ricardo, Delgado-Chávez, Ricardo, Mukherjee, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611594/
https://www.ncbi.nlm.nih.gov/pubmed/36287840
http://dx.doi.org/10.3390/toxics10100559

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