Designed Ankyrin Repeat Proteins: A New Class of Viral Entry Inhibitors

Designed ankyrin repeat proteins (DARPins) are engineered proteins comprising consensus designed ankyrin repeats as scaffold. Tightly packed repeats form a continuous hydrophobic core and a large groove-like solvent-accessible surface that creates a binding surface. DARPin domains recognizing a targ...

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Detalles Bibliográficos
Autores principales: Walser, Marcel, Mayor, Jennifer, Rothenberger, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611651/
https://www.ncbi.nlm.nih.gov/pubmed/36298797
http://dx.doi.org/10.3390/v14102242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611651/
https://www.ncbi.nlm.nih.gov/pubmed/36298797
http://dx.doi.org/10.3390/v14102242

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