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Proteomic clustering reveals the kinetics of disease biomarkers in bovine and human models of post-traumatic osteoarthritis

OBJECTIVES: In this study, we apply a clustering method to proteomic data sets from bovine and human models of post-traumatic osteoarthritis (PTOA) to distinguish clusters of proteins based on their kinetics of release from cartilage and examined these groups for PTOA biomarker candidates. We then q...

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Detalles Bibliográficos
Autores principales: Black, Rebecca Mae, Wang, Yang, Struglics, André, Lorenzo, Pilar, Chubinskaya, Susan, Grodzinsky, Alan J., Önnerfjord, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611763/
https://www.ncbi.nlm.nih.gov/pubmed/36313736
http://dx.doi.org/10.1016/j.ocarto.2021.100191

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