Mechanisms of P-Glycoprotein Regulation Under Exogenous and Endogenous Oxidative Stress In Vitro

We investigated the mechanisms of P-glycoprotein (P-gp) transporter regulation in Caco-2 cells under exogenous and endogenous oxidative stress (OS). Exogenous OS was modeled by exposure of the growth medium to hydrogen peroxide at concentrations of 0.1, 0.5, and 1 μM for 24 h or 10 μM for 72 h. Endo...

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Detalles Bibliográficos
Autores principales: Abalenikhina, Yu. V., Shchulkin, A. V., Mylnikov, P. Yu., Rokunov, E. D., Yakusheva, E. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611862/
https://www.ncbi.nlm.nih.gov/pubmed/36348721
http://dx.doi.org/10.32607/actanaturae.11759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611862/
https://www.ncbi.nlm.nih.gov/pubmed/36348721
http://dx.doi.org/10.32607/actanaturae.11759

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