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Biotransformation of Modified Benzylisoquinoline Alkaloids: Boldine and Berberine and In Silico Molecular Docking Studies of Metabolites on Telomerase and Human Protein Tyrosine Phosphatase 1B

Natural nitrogen heterocycles biotransformation has been extensively used to prepare synthetic drugs and explore the fate of therapeutic agents inside the body. Herein, the ability of filamentous fungi to biotransform boldine and berberine was investigated. Docking simulation studies of boldine, ber...

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Detalles Bibliográficos
Autores principales: Eliwa, Duaa, Ibrahim, Abdel-Rahim S., Kabbash, Amal, El-Aasr, Mona, Tomczyk, Michał, Bin Jardan, Yousef A., Batiha, Gaber El-Saber, Ragab, Amany E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611891/
https://www.ncbi.nlm.nih.gov/pubmed/36297307
http://dx.doi.org/10.3390/ph15101195