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Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica

The nicotinic acetylcholine receptors (nAChRs) are prototypical ligand-gated ion channels, provide cholinergic signaling, and are modulated by various venom toxins and drugs in addition to neurotransmitters. Here, four APETx-like toxins, including two new toxins, named Hmg 1b-2 Met(ox) and Hmg 1b-5,...

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Detalles Bibliográficos
Autores principales: Kalina, Rimma S., Kasheverov, Igor E., Koshelev, Sergey G., Sintsova, Oksana V., Peigneur, Steve, Pinheiro-Junior, Ernesto Lopes, Popov, Roman S., Chausova, Victoria E., Monastyrnaya, Margarita M., Dmitrenok, Pavel S., Isaeva, Marina P., Tytgat, Jan, Kozlov, Sergey A., Kozlovskaya, Emma P., Leychenko, Elena V., Gladkikh, Irina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611977/
https://www.ncbi.nlm.nih.gov/pubmed/36287966
http://dx.doi.org/10.3390/toxins14100697