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Structural Prediction and Characterization of Canavalia grandiflora (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins
A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the use of lectins as tools for recognition and therapy...
Autores principales: | Leal, Rodrigo Bainy, Mann, Josiane, Pinto-Junior, Vanir Reis, Oliveira, Messias Vital, Osterne, Vinicius Jose Silva, Wolin, Ingrid Alessandra Victoria, Nascimento, Ana Paula Machado, Welter, Priscilla Gomes, Ferreira, Valeria Maria Sousa, Silva, Alice Araujo, Seeger, Rodrigo Lopes, Nascimento, Kyria Santiago, Cavada, Benildo Sousa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612022/ https://www.ncbi.nlm.nih.gov/pubmed/36296679 http://dx.doi.org/10.3390/molecules27207089 |
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