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Simultaneous Determination of Methylated Nucleosides by HILIC–MS/MS Revealed Their Alterations in Urine from Breast Cancer Patients

RNA methylation plays a vital role in the pathogenesis of a variety of diseases including cancer, and aberrant levels of modified nucleosides in RNA were revealed to be related to cancer. Urine is a favored source for biomarker discovery due to the non-invasion to patients. Herein, we developed a se...

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Detalles Bibliográficos
Autores principales: Fang, Zhihao, Hu, Yiqiu, Hong, Xiujuan, Zhang, Xiaoxiao, Pan, Tao, Pan, Chi, Zheng, Shu, Guo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612034/
https://www.ncbi.nlm.nih.gov/pubmed/36295875
http://dx.doi.org/10.3390/metabo12100973