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High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs

(1) Background: High-altitude hypoxia has been shown to affect the pharmacokinetic properties of drugs. Although there is a high incidence of cardiovascular disease among individuals living in high-altitude areas, studies on the effect of high-altitude hypoxia on the pharmacokinetic properties of ca...

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Detalles Bibliográficos
Autores principales: Zhu, Junbo, Duan, Yabin, Duo, Delong, Yang, Jianxin, Bai, Xue, Liu, Guiqin, Wang, Qian, Wang, Xuejun, Qu, Ning, Zhou, Yang, Li, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612038/
https://www.ncbi.nlm.nih.gov/pubmed/36297415
http://dx.doi.org/10.3390/ph15101303