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Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome

Immunization is the best protection against chickenpox, measles and rubella. It is important to identify and immunize susceptible healthcare workers to prevent and control hospital infections. Our aim was to estimate the susceptibility level of healthcare workers at a Teaching Hospital in Rome conce...

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Autores principales: La Torre, Giuseppe, Marte, Mattia, Imeshtari, Valentin, Colaprico, Corrado, Ricci, Eleonora, Shaholli, David, Barletta, Vanessa India, Serruto, Pasquale, Gaeta, Aurelia, Antonelli, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612096/
https://www.ncbi.nlm.nih.gov/pubmed/36298438
http://dx.doi.org/10.3390/vaccines10101573
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author La Torre, Giuseppe
Marte, Mattia
Imeshtari, Valentin
Colaprico, Corrado
Ricci, Eleonora
Shaholli, David
Barletta, Vanessa India
Serruto, Pasquale
Gaeta, Aurelia
Antonelli, Guido
author_facet La Torre, Giuseppe
Marte, Mattia
Imeshtari, Valentin
Colaprico, Corrado
Ricci, Eleonora
Shaholli, David
Barletta, Vanessa India
Serruto, Pasquale
Gaeta, Aurelia
Antonelli, Guido
author_sort La Torre, Giuseppe
collection PubMed
description Immunization is the best protection against chickenpox, measles and rubella. It is important to identify and immunize susceptible healthcare workers to prevent and control hospital infections. Our aim was to estimate the susceptibility level of healthcare workers at a Teaching Hospital in Rome concerning these diseases and the factors associated to the susceptibility. Methods: a cross sectional study was carried out at the Department of Occupational Medicine of the Umberto I General Hospital of Rome. Participants were recruited during routine occupational health surveillance. As far as inclusion criteria, the following professionals were considered: doctors, nurses, laboratory technicians and other health professionals. Concerning the exclusion criteria, patients with HIV, cancer and diseases of the immune system, and acute illness or fever more than 38.5 °C, were not included in the study. A blood sample was tested for the presence of antibodies against measles, rubella and chicken pox. Results: 1106 healthcare professionals were involved in the study (41.8% nurses, 30.4% doctors, 12.3% laboratory technicians, 15.1% other health professionals): 25 (2.3%), 73 (6.6%) and 35 (3.2%) of these were susceptible to measles, rubella and chicken pox, respectively. The only variable associated with susceptibility of measles was age (p < 0.001). Furthermore, there was evidence of an association between various susceptibilities, particularly between measles and chickenpox (OR: 4.38). Conclusion: this study showed that even if the majority of our healthcare professionals are immunized for MRV, it is necessary not to underestimate the seronegativity of non-immune ones. All health professionals should be vaccinated to ensure safety for patients, especially the weakest.
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spelling pubmed-96120962022-10-28 Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome La Torre, Giuseppe Marte, Mattia Imeshtari, Valentin Colaprico, Corrado Ricci, Eleonora Shaholli, David Barletta, Vanessa India Serruto, Pasquale Gaeta, Aurelia Antonelli, Guido Vaccines (Basel) Article Immunization is the best protection against chickenpox, measles and rubella. It is important to identify and immunize susceptible healthcare workers to prevent and control hospital infections. Our aim was to estimate the susceptibility level of healthcare workers at a Teaching Hospital in Rome concerning these diseases and the factors associated to the susceptibility. Methods: a cross sectional study was carried out at the Department of Occupational Medicine of the Umberto I General Hospital of Rome. Participants were recruited during routine occupational health surveillance. As far as inclusion criteria, the following professionals were considered: doctors, nurses, laboratory technicians and other health professionals. Concerning the exclusion criteria, patients with HIV, cancer and diseases of the immune system, and acute illness or fever more than 38.5 °C, were not included in the study. A blood sample was tested for the presence of antibodies against measles, rubella and chicken pox. Results: 1106 healthcare professionals were involved in the study (41.8% nurses, 30.4% doctors, 12.3% laboratory technicians, 15.1% other health professionals): 25 (2.3%), 73 (6.6%) and 35 (3.2%) of these were susceptible to measles, rubella and chicken pox, respectively. The only variable associated with susceptibility of measles was age (p < 0.001). Furthermore, there was evidence of an association between various susceptibilities, particularly between measles and chickenpox (OR: 4.38). Conclusion: this study showed that even if the majority of our healthcare professionals are immunized for MRV, it is necessary not to underestimate the seronegativity of non-immune ones. All health professionals should be vaccinated to ensure safety for patients, especially the weakest. MDPI 2022-09-20 /pmc/articles/PMC9612096/ /pubmed/36298438 http://dx.doi.org/10.3390/vaccines10101573 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
La Torre, Giuseppe
Marte, Mattia
Imeshtari, Valentin
Colaprico, Corrado
Ricci, Eleonora
Shaholli, David
Barletta, Vanessa India
Serruto, Pasquale
Gaeta, Aurelia
Antonelli, Guido
Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title_full Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title_fullStr Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title_full_unstemmed Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title_short Susceptibility towards Chickenpox, Measles and Rubella among Healthcare Workers at a Teaching Hospital in Rome
title_sort susceptibility towards chickenpox, measles and rubella among healthcare workers at a teaching hospital in rome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612096/
https://www.ncbi.nlm.nih.gov/pubmed/36298438
http://dx.doi.org/10.3390/vaccines10101573
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