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Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions

Due to the presence of cationic units interpolyelectrolyte complexes (IPECs) can be used as a universal basis for preparation of biocidal coatings on different surfaces. Metallopolymer nanocomposites were successfully synthesized in irradiated solutions of polyacrylic acid (PAA) and polyethylenimine...

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Autores principales: Mkrtchyan, Kristina V., Pigareva, Vladislava A., Zezina, Elena A., Kuznetsova, Oksana A., Semenova, Anastasia A., Yushina, Yuliya K., Tolordava, Etery R., Grudistova, Maria A., Sybachin, Andrey V., Klimov, Dmitry I., Abramchuk, Sergey S., Yaroslavov, Alexander A., Zezin, Alexey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612164/
https://www.ncbi.nlm.nih.gov/pubmed/36297995
http://dx.doi.org/10.3390/polym14204417
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author Mkrtchyan, Kristina V.
Pigareva, Vladislava A.
Zezina, Elena A.
Kuznetsova, Oksana A.
Semenova, Anastasia A.
Yushina, Yuliya K.
Tolordava, Etery R.
Grudistova, Maria A.
Sybachin, Andrey V.
Klimov, Dmitry I.
Abramchuk, Sergey S.
Yaroslavov, Alexander A.
Zezin, Alexey A.
author_facet Mkrtchyan, Kristina V.
Pigareva, Vladislava A.
Zezina, Elena A.
Kuznetsova, Oksana A.
Semenova, Anastasia A.
Yushina, Yuliya K.
Tolordava, Etery R.
Grudistova, Maria A.
Sybachin, Andrey V.
Klimov, Dmitry I.
Abramchuk, Sergey S.
Yaroslavov, Alexander A.
Zezin, Alexey A.
author_sort Mkrtchyan, Kristina V.
collection PubMed
description Due to the presence of cationic units interpolyelectrolyte complexes (IPECs) can be used as a universal basis for preparation of biocidal coatings on different surfaces. Metallopolymer nanocomposites were successfully synthesized in irradiated solutions of polyacrylic acid (PAA) and polyethylenimine (PEI), and dispersions of non-stoichiometric IPECs of PAA–PEI containing silver ions. The data from turbidimetric titration and dynamic light scattering showed that pH 6 is the optimal value for obtaining IPECs. Metal polymer complexes based on IPEC with a PAA/PEI ratio equal to 3/1 and 1/3 were selected for synthesis of nanocomposites due to their aggregative stability. Studies using methods of UV–VIS spectroscopy and TEM have demonstrated that the size and spatial organization of silver nanoparticles depend on the composition of polymer systems. The average sizes of nanoparticles are 5 nm and 20 nm for complexes with a molar ratio of PAA/PEI units equal to 3/1 and 1/3, respectively. The synthesized nanocomposites were applied to the glass surface and exhibited high antibacterial activity against both gram-positive (Staphylococcus aureus) and gram-negative bacteria (Salmonella). It is shown that IPEC-Ag coatings demonstrate significantly more pronounced biocidal activity not only in comparison with macromolecular complexes of PAA–PEI, but also coatings of PEI and PEI based nanocomposites.
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spelling pubmed-96121642022-10-28 Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions Mkrtchyan, Kristina V. Pigareva, Vladislava A. Zezina, Elena A. Kuznetsova, Oksana A. Semenova, Anastasia A. Yushina, Yuliya K. Tolordava, Etery R. Grudistova, Maria A. Sybachin, Andrey V. Klimov, Dmitry I. Abramchuk, Sergey S. Yaroslavov, Alexander A. Zezin, Alexey A. Polymers (Basel) Article Due to the presence of cationic units interpolyelectrolyte complexes (IPECs) can be used as a universal basis for preparation of biocidal coatings on different surfaces. Metallopolymer nanocomposites were successfully synthesized in irradiated solutions of polyacrylic acid (PAA) and polyethylenimine (PEI), and dispersions of non-stoichiometric IPECs of PAA–PEI containing silver ions. The data from turbidimetric titration and dynamic light scattering showed that pH 6 is the optimal value for obtaining IPECs. Metal polymer complexes based on IPEC with a PAA/PEI ratio equal to 3/1 and 1/3 were selected for synthesis of nanocomposites due to their aggregative stability. Studies using methods of UV–VIS spectroscopy and TEM have demonstrated that the size and spatial organization of silver nanoparticles depend on the composition of polymer systems. The average sizes of nanoparticles are 5 nm and 20 nm for complexes with a molar ratio of PAA/PEI units equal to 3/1 and 1/3, respectively. The synthesized nanocomposites were applied to the glass surface and exhibited high antibacterial activity against both gram-positive (Staphylococcus aureus) and gram-negative bacteria (Salmonella). It is shown that IPEC-Ag coatings demonstrate significantly more pronounced biocidal activity not only in comparison with macromolecular complexes of PAA–PEI, but also coatings of PEI and PEI based nanocomposites. MDPI 2022-10-19 /pmc/articles/PMC9612164/ /pubmed/36297995 http://dx.doi.org/10.3390/polym14204417 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mkrtchyan, Kristina V.
Pigareva, Vladislava A.
Zezina, Elena A.
Kuznetsova, Oksana A.
Semenova, Anastasia A.
Yushina, Yuliya K.
Tolordava, Etery R.
Grudistova, Maria A.
Sybachin, Andrey V.
Klimov, Dmitry I.
Abramchuk, Sergey S.
Yaroslavov, Alexander A.
Zezin, Alexey A.
Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title_full Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title_fullStr Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title_full_unstemmed Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title_short Preparation of Biocidal Nanocomposites in X-ray Irradiated Interpolyelectolyte Complexes of Polyacrylic Acid and Polyethylenimine with Ag-Ions
title_sort preparation of biocidal nanocomposites in x-ray irradiated interpolyelectolyte complexes of polyacrylic acid and polyethylenimine with ag-ions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612164/
https://www.ncbi.nlm.nih.gov/pubmed/36297995
http://dx.doi.org/10.3390/polym14204417
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