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Pretargeted Imaging beyond the Blood–Brain Barrier—Utopia or Feasible?

Pretargeting is a promising nuclear imaging technique that allows for the usage of antibodies (Abs) with enhanced imaging contrast and reduced patient radiation burden. It is based on bioorthogonal chemistry with the tetrazine ligation—a reaction between trans-cyclooctenes (TCOs) and tetrazines (Tzs...

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Detalles Bibliográficos
Autores principales: Lopes van den Broek, Sara, Shalgunov, Vladimir, García Vázquez, Rocío, Beschorner, Natalie, Bidesi, Natasha S. R., Nedergaard, Maiken, Knudsen, Gitte M., Sehlin, Dag, Syvänen, Stina, Herth, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612205/
https://www.ncbi.nlm.nih.gov/pubmed/36297303
http://dx.doi.org/10.3390/ph15101191