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Pretargeted Imaging beyond the Blood–Brain Barrier—Utopia or Feasible?
Pretargeting is a promising nuclear imaging technique that allows for the usage of antibodies (Abs) with enhanced imaging contrast and reduced patient radiation burden. It is based on bioorthogonal chemistry with the tetrazine ligation—a reaction between trans-cyclooctenes (TCOs) and tetrazines (Tzs...
Autores principales: | Lopes van den Broek, Sara, Shalgunov, Vladimir, García Vázquez, Rocío, Beschorner, Natalie, Bidesi, Natasha S. R., Nedergaard, Maiken, Knudsen, Gitte M., Sehlin, Dag, Syvänen, Stina, Herth, Matthias M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612205/ https://www.ncbi.nlm.nih.gov/pubmed/36297303 http://dx.doi.org/10.3390/ph15101191 |
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