Antileishmanial Anthracene Endoperoxides: Efficacy In Vitro, Mechanisms and Structure-Activity Relationships

Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells. Therefore, we studied in this work a set of new anthracene-derived EP (AcEP) together with their non-endoperoxidic anal...

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Detalles Bibliográficos
Autores principales: Machin, Laura, Piontek, Martin, Todhe, Sara, Staniek, Katrin, Monzote, Lianet, Fudickar, Werner, Linker, Torsten, Gille, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612231/
https://www.ncbi.nlm.nih.gov/pubmed/36296439
http://dx.doi.org/10.3390/molecules27206846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612231/
https://www.ncbi.nlm.nih.gov/pubmed/36296439
http://dx.doi.org/10.3390/molecules27206846

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