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Antileishmanial Anthracene Endoperoxides: Efficacy In Vitro, Mechanisms and Structure-Activity Relationships
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells. Therefore, we studied in this work a set of new anthracene-derived EP (AcEP) together with their non-endoperoxidic anal...
Autores principales: | Machin, Laura, Piontek, Martin, Todhe, Sara, Staniek, Katrin, Monzote, Lianet, Fudickar, Werner, Linker, Torsten, Gille, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612231/ https://www.ncbi.nlm.nih.gov/pubmed/36296439 http://dx.doi.org/10.3390/molecules27206846 |
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