The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection

From December 2021 to May 2022, the Omicron BA.1 and BA.2 subvariants successively became the most dominant strains in many countries around the world. Subsequently, Omicron subvariants have emerged, and Omicron has been classified into five main lineages, including BA.1, BA.2, BA.3, BA.4, BA.5, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Dandan, Nie, Wenjian, Sun, Yanhong, Ye, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612321/
https://www.ncbi.nlm.nih.gov/pubmed/36298564
http://dx.doi.org/10.3390/vaccines10101699
_version_ 1784819745915142144
author Tian, Dandan
Nie, Wenjian
Sun, Yanhong
Ye, Qing
author_facet Tian, Dandan
Nie, Wenjian
Sun, Yanhong
Ye, Qing
author_sort Tian, Dandan
collection PubMed
description From December 2021 to May 2022, the Omicron BA.1 and BA.2 subvariants successively became the most dominant strains in many countries around the world. Subsequently, Omicron subvariants have emerged, and Omicron has been classified into five main lineages, including BA.1, BA.2, BA.3, BA.4, BA.5, and some sublineages (BA.1.1, BA.2.12.1, BA.2.11, BA.2.75, BA.4.6, BA.5.1, and BA.5.2). The recent emergence of several Omicron subvariants has generated new concerns about further escape from immunity induced by prior infection and vaccination and the creation of new COVID-19 waves globally. In particular, BA.5 (first found in southern Africa, February 2022) displays a higher transmissibility than other Omicron subvariants and is replacing the previously circulating BA.1 and BA.2 in several countries.
format Online
Article
Text
id pubmed-9612321
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96123212022-10-28 The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection Tian, Dandan Nie, Wenjian Sun, Yanhong Ye, Qing Vaccines (Basel) Review From December 2021 to May 2022, the Omicron BA.1 and BA.2 subvariants successively became the most dominant strains in many countries around the world. Subsequently, Omicron subvariants have emerged, and Omicron has been classified into five main lineages, including BA.1, BA.2, BA.3, BA.4, BA.5, and some sublineages (BA.1.1, BA.2.12.1, BA.2.11, BA.2.75, BA.4.6, BA.5.1, and BA.5.2). The recent emergence of several Omicron subvariants has generated new concerns about further escape from immunity induced by prior infection and vaccination and the creation of new COVID-19 waves globally. In particular, BA.5 (first found in southern Africa, February 2022) displays a higher transmissibility than other Omicron subvariants and is replacing the previously circulating BA.1 and BA.2 in several countries. MDPI 2022-10-11 /pmc/articles/PMC9612321/ /pubmed/36298564 http://dx.doi.org/10.3390/vaccines10101699 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tian, Dandan
Nie, Wenjian
Sun, Yanhong
Ye, Qing
The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title_full The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title_fullStr The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title_full_unstemmed The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title_short The Epidemiological Features of the SARS-CoV-2 Omicron Subvariant BA.5 and Its Evasion of the Neutralizing Activity of Vaccination and Prior Infection
title_sort epidemiological features of the sars-cov-2 omicron subvariant ba.5 and its evasion of the neutralizing activity of vaccination and prior infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612321/
https://www.ncbi.nlm.nih.gov/pubmed/36298564
http://dx.doi.org/10.3390/vaccines10101699
work_keys_str_mv AT tiandandan theepidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT niewenjian theepidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT sunyanhong theepidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT yeqing theepidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT tiandandan epidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT niewenjian epidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT sunyanhong epidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection
AT yeqing epidemiologicalfeaturesofthesarscov2omicronsubvariantba5anditsevasionoftheneutralizingactivityofvaccinationandpriorinfection

Ejemplares similares