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The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease

Cyclosporine A (CSA) is an immunosuppressive drug that has improved transplant survival rates. However, its use is often limited because it is thought to be linked to the development of chronic kidney disease after kidney transplants. This study aimed to investigate the protective effects and underl...

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Detalles Bibliográficos
Autores principales: Marghani, Basma H., El-Adl, Mohamed, Ateya, Ahmed I., Othman, Basma H., Ghamry, Heba I., Shukry, Mustafa, Soliman, Mohamed Mohamed, Rizk, Mohamed Abdo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612357/
https://www.ncbi.nlm.nih.gov/pubmed/36295901
http://dx.doi.org/10.3390/metabo12100999