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Stress and viral insults do not trigger E200K PrP conversion in human cerebral organoids

Prion diseases are a group of rare, transmissible, and invariably fatal neurodegenerative diseases that affect both humans and animals. The cause of these diseases is misfolding of the prion protein into pathological isoforms called prions. Of all human prion diseases, 10–15% of cases are genetic an...

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Detalles Bibliográficos
Autores principales:	Smith, Anna, Groveman, Bradley R., Winkler, Clayton, Williams, Katie, Walters, Ryan, Yuan, Jue, Zou, Wenquan, Peterson, Karin, Foliaki, Simote T., Haigh, Cathryn L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612459/ https://www.ncbi.nlm.nih.gov/pubmed/36301953 http://dx.doi.org/10.1371/journal.pone.0277051

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