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BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data

In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which ref...

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Detalles Bibliográficos
Autor principal: Chen, Li-Pang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612554/
https://www.ncbi.nlm.nih.gov/pubmed/36301828
http://dx.doi.org/10.1371/journal.pone.0276664
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author Chen, Li-Pang
author_facet Chen, Li-Pang
author_sort Chen, Li-Pang
collection PubMed
description In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which refers to BOOsting algorithm for Measurement Error in binary responses and ultrahigh-dimensional predictors. We primarily focus on logistic regression and probit models with responses, predictors, or both contaminated with measurement error. The BOOME aims to address measurement error effects, and employ boosting procedure to make variable selection and estimation.
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spelling pubmed-96125542022-10-28 BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data Chen, Li-Pang PLoS One Research Article In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which refers to BOOsting algorithm for Measurement Error in binary responses and ultrahigh-dimensional predictors. We primarily focus on logistic regression and probit models with responses, predictors, or both contaminated with measurement error. The BOOME aims to address measurement error effects, and employ boosting procedure to make variable selection and estimation. Public Library of Science 2022-10-27 /pmc/articles/PMC9612554/ /pubmed/36301828 http://dx.doi.org/10.1371/journal.pone.0276664 Text en © 2022 Li-Pang Chen https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Chen, Li-Pang
BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title_full BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title_fullStr BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title_full_unstemmed BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title_short BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
title_sort boome: a python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612554/
https://www.ncbi.nlm.nih.gov/pubmed/36301828
http://dx.doi.org/10.1371/journal.pone.0276664
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