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BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data
In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which ref...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612554/ https://www.ncbi.nlm.nih.gov/pubmed/36301828 http://dx.doi.org/10.1371/journal.pone.0276664 |
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author | Chen, Li-Pang |
author_facet | Chen, Li-Pang |
author_sort | Chen, Li-Pang |
collection | PubMed |
description | In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which refers to BOOsting algorithm for Measurement Error in binary responses and ultrahigh-dimensional predictors. We primarily focus on logistic regression and probit models with responses, predictors, or both contaminated with measurement error. The BOOME aims to address measurement error effects, and employ boosting procedure to make variable selection and estimation. |
format | Online Article Text |
id | pubmed-9612554 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-96125542022-10-28 BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data Chen, Li-Pang PLoS One Research Article In gene expression data analysis framework, ultrahigh dimensionality and measurement error are ubiquitous features. Therefore, it is crucial to correct measurement error effects and make variable selection when fitting a regression model. In this paper, we introduce a python package BOOME, which refers to BOOsting algorithm for Measurement Error in binary responses and ultrahigh-dimensional predictors. We primarily focus on logistic regression and probit models with responses, predictors, or both contaminated with measurement error. The BOOME aims to address measurement error effects, and employ boosting procedure to make variable selection and estimation. Public Library of Science 2022-10-27 /pmc/articles/PMC9612554/ /pubmed/36301828 http://dx.doi.org/10.1371/journal.pone.0276664 Text en © 2022 Li-Pang Chen https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Chen, Li-Pang BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title | BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title_full | BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title_fullStr | BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title_full_unstemmed | BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title_short | BOOME: A Python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
title_sort | boome: a python package for handling misclassified disease and ultrahigh-dimensional error-prone gene expression data |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612554/ https://www.ncbi.nlm.nih.gov/pubmed/36301828 http://dx.doi.org/10.1371/journal.pone.0276664 |
work_keys_str_mv | AT chenlipang boomeapythonpackageforhandlingmisclassifieddiseaseandultrahighdimensionalerrorpronegeneexpressiondata |