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Pulmonary Manifestations in Rheumatological Diseases

Pulmonary involvement complicates the various aspects of care in patients suffering from autoimmune disorders. The epidemiological data generated over the last 10 to 15 years have improved the overall understanding of the risk factors and pathophysiological mechanisms involved in pulmonary involveme...

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Autores principales: Aurangabadkar, Gaurang M, Aurangabadkar, Milind Y, Choudhary, Sumer S, Ali, Saood N, Khan, Shafee M, Jadhav, Ulhas S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612897/
https://www.ncbi.nlm.nih.gov/pubmed/36321051
http://dx.doi.org/10.7759/cureus.29628
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author Aurangabadkar, Gaurang M
Aurangabadkar, Milind Y
Choudhary, Sumer S
Ali, Saood N
Khan, Shafee M
Jadhav, Ulhas S
author_facet Aurangabadkar, Gaurang M
Aurangabadkar, Milind Y
Choudhary, Sumer S
Ali, Saood N
Khan, Shafee M
Jadhav, Ulhas S
author_sort Aurangabadkar, Gaurang M
collection PubMed
description Pulmonary involvement complicates the various aspects of care in patients suffering from autoimmune disorders. The epidemiological data generated over the last 10 to 15 years have improved the overall understanding of the risk factors and pathophysiological mechanisms involved in pulmonary involvement in rheumatological conditions. Recent advances in genetics have provided superior insight into the pathogenesis of autoimmune diseases and the underlying pulmonary involvement. This review article provides a concise overview of the four most common rheumatological conditions associated with pulmonary involvement: systemic lupus erythematosus (SLE), dermatomyositis/polymyositis, rheumatoid arthritis (RA), and systemic sclerosis (SSc). The clinical, epidemiological, and genetic aspects of these diseases are summarized in this article with particular emphasis on the characteristic patterns of pulmonary involvement in radiological imaging and various treatment options for each of these autoimmune diseases and their lung manifestations.
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spelling pubmed-96128972022-10-31 Pulmonary Manifestations in Rheumatological Diseases Aurangabadkar, Gaurang M Aurangabadkar, Milind Y Choudhary, Sumer S Ali, Saood N Khan, Shafee M Jadhav, Ulhas S Cureus Internal Medicine Pulmonary involvement complicates the various aspects of care in patients suffering from autoimmune disorders. The epidemiological data generated over the last 10 to 15 years have improved the overall understanding of the risk factors and pathophysiological mechanisms involved in pulmonary involvement in rheumatological conditions. Recent advances in genetics have provided superior insight into the pathogenesis of autoimmune diseases and the underlying pulmonary involvement. This review article provides a concise overview of the four most common rheumatological conditions associated with pulmonary involvement: systemic lupus erythematosus (SLE), dermatomyositis/polymyositis, rheumatoid arthritis (RA), and systemic sclerosis (SSc). The clinical, epidemiological, and genetic aspects of these diseases are summarized in this article with particular emphasis on the characteristic patterns of pulmonary involvement in radiological imaging and various treatment options for each of these autoimmune diseases and their lung manifestations. Cureus 2022-09-26 /pmc/articles/PMC9612897/ /pubmed/36321051 http://dx.doi.org/10.7759/cureus.29628 Text en Copyright © 2022, Aurangabadkar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Aurangabadkar, Gaurang M
Aurangabadkar, Milind Y
Choudhary, Sumer S
Ali, Saood N
Khan, Shafee M
Jadhav, Ulhas S
Pulmonary Manifestations in Rheumatological Diseases
title Pulmonary Manifestations in Rheumatological Diseases
title_full Pulmonary Manifestations in Rheumatological Diseases
title_fullStr Pulmonary Manifestations in Rheumatological Diseases
title_full_unstemmed Pulmonary Manifestations in Rheumatological Diseases
title_short Pulmonary Manifestations in Rheumatological Diseases
title_sort pulmonary manifestations in rheumatological diseases
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612897/
https://www.ncbi.nlm.nih.gov/pubmed/36321051
http://dx.doi.org/10.7759/cureus.29628
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