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Excitatory and inhibitory D-serine binding to the NMDA receptor

N-methyl-D-aspartate receptors (NMDARs) uniquely require binding of two different neurotransmitter agonists for synaptic transmission. D-serine and glycine bind to one subunit, GluN1, while glutamate binds to the other, GluN2. These agonists bind to the receptor’s bi-lobed ligand-binding domains (LB...

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Detalles Bibliográficos
Autores principales:	Yovanno, Remy A, Chou, Tsung Han, Brantley, Sarah J, Furukawa, Hiro, Lau, Albert Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612912/ https://www.ncbi.nlm.nih.gov/pubmed/36301074 http://dx.doi.org/10.7554/eLife.77645

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