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The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack

INTRODUCTION: Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemic attack (TIA). Conversion of clopidogrel to its active metabolite by hepatic cytochrome P450-2C19 (CYP2C19) is essential for the inhibition of the P2Y12 receptor and...

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Detalles Bibliográficos
Autores principales:	McDermott, John H, Leach, Marc, Sen, Dwaipayan, Smith, Craig J., Newman, William G., Bath, Philip M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9612933/ https://www.ncbi.nlm.nih.gov/pubmed/35912831 http://dx.doi.org/10.1080/17512433.2022.2108401

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