Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults

We carried out integrated host and pathogen metagenomic RNA and DNA next generation sequencing (mNGS) of whole blood (n = 221) and plasma (n = 138) from critically ill patients following hospital admission. We assigned patients into sepsis groups on the basis of clinical and microbiological criteria...

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Detalles Bibliográficos
Autores principales: Kalantar, Katrina L., Neyton, Lucile, Abdelghany, Mazin, Mick, Eran, Jauregui, Alejandra, Caldera, Saharai, Serpa, Paula Hayakawa, Ghale, Rajani, Albright, Jack, Sarma, Aartik, Tsitsiklis, Alexandra, Leligdowicz, Aleksandra, Christenson, Stephanie A., Liu, Kathleen, Kangelaris, Kirsten N., Hendrickson, Carolyn, Sinha, Pratik, Gomez, Antonio, Neff, Norma, Pisco, Angela, Doernberg, Sarah B., Derisi, Joseph L., Matthay, Michael A., Calfee, Carolyn S., Langelier, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613463/
https://www.ncbi.nlm.nih.gov/pubmed/36266337
http://dx.doi.org/10.1038/s41564-022-01237-2

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