A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome

Many cancers are organized as cellular hierarchies sustained by cancer stem cells (CSC), whose eradication is crucial for achieving long-term remission. Difficulties to isolate and undertake in vitro and in vivo experimental studies of rare CSC under conditions that preserve their original propertie...

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Detalles Bibliográficos
Autores principales: Boutzen, Héléna, Madani Tonekaboni, Seyed Ali, Chan-Seng-Yue, Michelle, Murison, Alex, Takayama, Naoya, Mbong, Nathan, Wagenblast, Elvin, Orouji, Elias, Arruda, Andrea, Mitchell, Amanda, Notta, Faiyaz, Minden, Mark D., Lupien, Mathieu, Kaufmann, Kerstin B., Dick, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613464/
https://www.ncbi.nlm.nih.gov/pubmed/36131042
http://dx.doi.org/10.1038/s41375-022-01697-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613464/
https://www.ncbi.nlm.nih.gov/pubmed/36131042
http://dx.doi.org/10.1038/s41375-022-01697-9

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