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Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia

PURPOSE: To investigate the clinical value of electrophysiological tests in indicating pathogenic vascular contact of the 8th nerve in definite vestibular paroxysmia (VP) cases to provide a reference for decompression surgery. METHODS: We retrospectively analyzed patients who had vertigo, unilateral...

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Autores principales: Sun, Huiying, Tian, Xu, Zhao, Yang, Jiang, Hong, Gao, Zhiqiang, Wu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613544/
https://www.ncbi.nlm.nih.gov/pubmed/35249141
http://dx.doi.org/10.1007/s00701-022-05157-2
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author Sun, Huiying
Tian, Xu
Zhao, Yang
Jiang, Hong
Gao, Zhiqiang
Wu, Haiyan
author_facet Sun, Huiying
Tian, Xu
Zhao, Yang
Jiang, Hong
Gao, Zhiqiang
Wu, Haiyan
author_sort Sun, Huiying
collection PubMed
description PURPOSE: To investigate the clinical value of electrophysiological tests in indicating pathogenic vascular contact of the 8th nerve in definite vestibular paroxysmia (VP) cases to provide a reference for decompression surgery. METHODS: We retrospectively analyzed patients who had vertigo, unilateral tinnitus, or hearing loss and exhibited vascular contact of the 8th cranial nerve by MRI. Participants were classified into the VP or non-VP group according to the criteria of the Bárány Society in 2016. The demographic characteristics and audiological and electrophysiological test results of the two groups were compared. Receiver operating characteristic (ROC) curves were calculated for ABR to determine the best parameters and cutoff values to predict the existence of pathological neurovascular contact in VP. RESULTS: Thirteen patients in the VP group and 66 patients in the non-VP group were included. VP patients had longer interpeak latency (IPL) I–III and wave III latency compared to non-VP patients (p < 0.001; p < 0.001). According to the ROC analyses, IPL I–III and wave III latency were the best indicators for the diagnosis of VP. The optimal cutoff for IPL I–III was 2.3 ms (sensitivity 84.6%, specificity 95.5%), and that for wave III latency was 4.0 ms (sensitivity 92.3%, specificity 77.3%). There were no differences in the PTA, caloric test, o-VEMP, or c-VEMP results between the two groups. CONCLUSION: Prolonged IPL I–III and the wave III latency of ABR strongly suggested that vascular contact of the 8th cranial nerve was pathological, which may provide some references for microvascular decompression surgery of VP. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00701-022-05157-2.
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spelling pubmed-96135442022-10-29 Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia Sun, Huiying Tian, Xu Zhao, Yang Jiang, Hong Gao, Zhiqiang Wu, Haiyan Acta Neurochir (Wien) Original Article - Neurosurgery general PURPOSE: To investigate the clinical value of electrophysiological tests in indicating pathogenic vascular contact of the 8th nerve in definite vestibular paroxysmia (VP) cases to provide a reference for decompression surgery. METHODS: We retrospectively analyzed patients who had vertigo, unilateral tinnitus, or hearing loss and exhibited vascular contact of the 8th cranial nerve by MRI. Participants were classified into the VP or non-VP group according to the criteria of the Bárány Society in 2016. The demographic characteristics and audiological and electrophysiological test results of the two groups were compared. Receiver operating characteristic (ROC) curves were calculated for ABR to determine the best parameters and cutoff values to predict the existence of pathological neurovascular contact in VP. RESULTS: Thirteen patients in the VP group and 66 patients in the non-VP group were included. VP patients had longer interpeak latency (IPL) I–III and wave III latency compared to non-VP patients (p < 0.001; p < 0.001). According to the ROC analyses, IPL I–III and wave III latency were the best indicators for the diagnosis of VP. The optimal cutoff for IPL I–III was 2.3 ms (sensitivity 84.6%, specificity 95.5%), and that for wave III latency was 4.0 ms (sensitivity 92.3%, specificity 77.3%). There were no differences in the PTA, caloric test, o-VEMP, or c-VEMP results between the two groups. CONCLUSION: Prolonged IPL I–III and the wave III latency of ABR strongly suggested that vascular contact of the 8th cranial nerve was pathological, which may provide some references for microvascular decompression surgery of VP. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00701-022-05157-2. Springer Vienna 2022-03-05 2022 /pmc/articles/PMC9613544/ /pubmed/35249141 http://dx.doi.org/10.1007/s00701-022-05157-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article - Neurosurgery general
Sun, Huiying
Tian, Xu
Zhao, Yang
Jiang, Hong
Gao, Zhiqiang
Wu, Haiyan
Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title_full Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title_fullStr Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title_full_unstemmed Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title_short Application of ABR in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
title_sort application of abr in pathogenic neurovascular compression of the 8th cranial nerve in vestibular paroxysmia
topic Original Article - Neurosurgery general
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613544/
https://www.ncbi.nlm.nih.gov/pubmed/35249141
http://dx.doi.org/10.1007/s00701-022-05157-2
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