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The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution

Osteoporotic vertebral compression fractures (OVCFs) have gradually become a health threat to elderly individuals. Treatment options are controversial, and many challenges remain. Our study aimed to investigate the management trends of OVCFs at a single institution, covering all cases of OVCFs betwe...

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Autores principales: Qin, Jie, Zhong, Weiyang, Quan, Zhengxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613630/
https://www.ncbi.nlm.nih.gov/pubmed/36302942
http://dx.doi.org/10.1038/s41598-022-23106-y
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author Qin, Jie
Zhong, Weiyang
Quan, Zhengxue
author_facet Qin, Jie
Zhong, Weiyang
Quan, Zhengxue
author_sort Qin, Jie
collection PubMed
description Osteoporotic vertebral compression fractures (OVCFs) have gradually become a health threat to elderly individuals. Treatment options are controversial, and many challenges remain. Our study aimed to investigate the management trends of OVCFs at a single institution, covering all cases of OVCFs between January 1, 2016, and December 31, 2020. A total of 938 OVCF patients were reviewed, and OVCFs were most common in patients over 70 years old. The hospital stay, surgery haemorrhage rate and total cost decreased year by year. The number of patients with previous OVCFs varied from 123 in 2016 to 83 in 2020. The average bone mineral density (BMD) of the patients generally decreased year by year. In OVCF treatments, the rate of PV or PK increased from 93.86% in 2016 to 98.98% in 2020, while the rate of PV combined with pedicle fixation decreased from 6.14% in 2012 to 1.12% in 2020. Most patients were treated with bisphosphonates, and only 2 patients were treated with teriparatide. The visual analogue scale scores significantly improved at the final follow-up compared with the preoperative values. The rate of previous fractures was correlated with BMD, while there were no correlations with sex, age, or anti-osteoporosis treatment. In conclusion, the 5-year incidence of OVCFs increased and average patient BMD worsened by year. Although the total cost is continuously decreasing, poor adherence to anti-osteoporosis treatments and the prevention of refracture create more severe challenges.
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spelling pubmed-96136302022-10-29 The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution Qin, Jie Zhong, Weiyang Quan, Zhengxue Sci Rep Article Osteoporotic vertebral compression fractures (OVCFs) have gradually become a health threat to elderly individuals. Treatment options are controversial, and many challenges remain. Our study aimed to investigate the management trends of OVCFs at a single institution, covering all cases of OVCFs between January 1, 2016, and December 31, 2020. A total of 938 OVCF patients were reviewed, and OVCFs were most common in patients over 70 years old. The hospital stay, surgery haemorrhage rate and total cost decreased year by year. The number of patients with previous OVCFs varied from 123 in 2016 to 83 in 2020. The average bone mineral density (BMD) of the patients generally decreased year by year. In OVCF treatments, the rate of PV or PK increased from 93.86% in 2016 to 98.98% in 2020, while the rate of PV combined with pedicle fixation decreased from 6.14% in 2012 to 1.12% in 2020. Most patients were treated with bisphosphonates, and only 2 patients were treated with teriparatide. The visual analogue scale scores significantly improved at the final follow-up compared with the preoperative values. The rate of previous fractures was correlated with BMD, while there were no correlations with sex, age, or anti-osteoporosis treatment. In conclusion, the 5-year incidence of OVCFs increased and average patient BMD worsened by year. Although the total cost is continuously decreasing, poor adherence to anti-osteoporosis treatments and the prevention of refracture create more severe challenges. Nature Publishing Group UK 2022-10-27 /pmc/articles/PMC9613630/ /pubmed/36302942 http://dx.doi.org/10.1038/s41598-022-23106-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Qin, Jie
Zhong, Weiyang
Quan, Zhengxue
The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title_full The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title_fullStr The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title_full_unstemmed The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title_short The surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
title_sort surgical management trends of osteoporotic vertebral compression fractures: 5-year experience in one institution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613630/
https://www.ncbi.nlm.nih.gov/pubmed/36302942
http://dx.doi.org/10.1038/s41598-022-23106-y
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