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Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac...

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Autores principales: Cullen, Louise, Collinson, Paul O, Giannitsis, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613856/
https://www.ncbi.nlm.nih.gov/pubmed/35017187
http://dx.doi.org/10.1136/emermed-2021-211907
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author Cullen, Louise
Collinson, Paul O
Giannitsis, Evangelos
author_facet Cullen, Louise
Collinson, Paul O
Giannitsis, Evangelos
author_sort Cullen, Louise
collection PubMed
description Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays.
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spelling pubmed-96138562022-10-29 Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities Cullen, Louise Collinson, Paul O Giannitsis, Evangelos Emerg Med J Practice Review Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays. BMJ Publishing Group 2022-11 2022-01-11 /pmc/articles/PMC9613856/ /pubmed/35017187 http://dx.doi.org/10.1136/emermed-2021-211907 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Practice Review
Cullen, Louise
Collinson, Paul O
Giannitsis, Evangelos
Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title_full Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title_fullStr Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title_full_unstemmed Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title_short Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
title_sort point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
topic Practice Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613856/
https://www.ncbi.nlm.nih.gov/pubmed/35017187
http://dx.doi.org/10.1136/emermed-2021-211907
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