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Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities
Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613856/ https://www.ncbi.nlm.nih.gov/pubmed/35017187 http://dx.doi.org/10.1136/emermed-2021-211907 |
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author | Cullen, Louise Collinson, Paul O Giannitsis, Evangelos |
author_facet | Cullen, Louise Collinson, Paul O Giannitsis, Evangelos |
author_sort | Cullen, Louise |
collection | PubMed |
description | Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays. |
format | Online Article Text |
id | pubmed-9613856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-96138562022-10-29 Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities Cullen, Louise Collinson, Paul O Giannitsis, Evangelos Emerg Med J Practice Review Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays. BMJ Publishing Group 2022-11 2022-01-11 /pmc/articles/PMC9613856/ /pubmed/35017187 http://dx.doi.org/10.1136/emermed-2021-211907 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Practice Review Cullen, Louise Collinson, Paul O Giannitsis, Evangelos Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title | Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title_full | Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title_fullStr | Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title_full_unstemmed | Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title_short | Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
title_sort | point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities |
topic | Practice Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613856/ https://www.ncbi.nlm.nih.gov/pubmed/35017187 http://dx.doi.org/10.1136/emermed-2021-211907 |
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