Expression of membrane Hsp90 is a molecular signature of T cell activation

Heat shock protein 90 (Hsp90) maintains cellular proteostasis during stress and has been under investigation as a therapeutic target in cancer for over two decades. We and others have identified a membrane expressed form of Hsp90 (mHsp90) that previously appeared to be restricted to rapidly prolifer...

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Detalles Bibliográficos
Autores principales: Scarneo, Scott A., Smith, Aaron P., Favret, Jacob, O’Connell, Robert, Pickeral, Joy, Yang, Kelly W., Ferrari, Guido, Loiselle, David R., Hughes, Philip F., Kulkarni, Manjusha M., Gargesha, Madhusudhana, Scott, Bryan, Roy, Debashish, Haynes, Barton F., Kwiek, Jesse J., Haystead, Timothy A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613876/
https://www.ncbi.nlm.nih.gov/pubmed/36302951
http://dx.doi.org/10.1038/s41598-022-22788-8

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