Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

The sarcomere is the functional unit of skeletal muscle, essential for proper contraction. Numerous acquired and inherited myopathies impact sarcomere function causing clinically significant disease. Mechanistic investigations of sarcomere activation have been challenging to undertake in the context...

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Detalles Bibliográficos
Autores principales: Martin, Ashley A., Thompson, Brian R., Davis, Jonathan P., Vang, Hluechy, Hahn, Dongwoo, Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613882/
https://www.ncbi.nlm.nih.gov/pubmed/36302792
http://dx.doi.org/10.1038/s41598-022-21425-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613882/
https://www.ncbi.nlm.nih.gov/pubmed/36302792
http://dx.doi.org/10.1038/s41598-022-21425-8

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