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Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers
The sarcomere is the functional unit of skeletal muscle, essential for proper contraction. Numerous acquired and inherited myopathies impact sarcomere function causing clinically significant disease. Mechanistic investigations of sarcomere activation have been challenging to undertake in the context...
Autores principales: | Martin, Ashley A., Thompson, Brian R., Davis, Jonathan P., Vang, Hluechy, Hahn, Dongwoo, Metzger, Joseph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613882/ https://www.ncbi.nlm.nih.gov/pubmed/36302792 http://dx.doi.org/10.1038/s41598-022-21425-8 |
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