Laboratory prognostic factors for the long-term survival of multiple system atrophy

To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate...

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Detalles Bibliográficos
Autores principales: Shin, Jung Hwan, Kim, Han-Joon, Lee, Chan Young, Chang, Hee Jin, Woo, Kyung Ah, Jeon, Beomseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613998/
https://www.ncbi.nlm.nih.gov/pubmed/36302764
http://dx.doi.org/10.1038/s41531-022-00413-9
Descripción
Sumario:To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate, and low hemoglobin, protein, albumin, and creatinine were correlated with higher mortality in MSA. Systemic alteration in inflammation and nutritional status in the early stage are associated with higher mortality in MSA.

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