Laboratory prognostic factors for the long-term survival of multiple system atrophy

To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate...

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Autores principales: Shin, Jung Hwan, Kim, Han-Joon, Lee, Chan Young, Chang, Hee Jin, Woo, Kyung Ah, Jeon, Beomseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613998/
https://www.ncbi.nlm.nih.gov/pubmed/36302764
http://dx.doi.org/10.1038/s41531-022-00413-9
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author Shin, Jung Hwan
Kim, Han-Joon
Lee, Chan Young
Chang, Hee Jin
Woo, Kyung Ah
Jeon, Beomseok
author_facet Shin, Jung Hwan
Kim, Han-Joon
Lee, Chan Young
Chang, Hee Jin
Woo, Kyung Ah
Jeon, Beomseok
author_sort Shin, Jung Hwan
collection PubMed
description To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate, and low hemoglobin, protein, albumin, and creatinine were correlated with higher mortality in MSA. Systemic alteration in inflammation and nutritional status in the early stage are associated with higher mortality in MSA.
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spelling pubmed-96139982022-10-29 Laboratory prognostic factors for the long-term survival of multiple system atrophy Shin, Jung Hwan Kim, Han-Joon Lee, Chan Young Chang, Hee Jin Woo, Kyung Ah Jeon, Beomseok NPJ Parkinsons Dis Brief Communication To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate, and low hemoglobin, protein, albumin, and creatinine were correlated with higher mortality in MSA. Systemic alteration in inflammation and nutritional status in the early stage are associated with higher mortality in MSA. Nature Publishing Group UK 2022-10-27 /pmc/articles/PMC9613998/ /pubmed/36302764 http://dx.doi.org/10.1038/s41531-022-00413-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Communication
Shin, Jung Hwan
Kim, Han-Joon
Lee, Chan Young
Chang, Hee Jin
Woo, Kyung Ah
Jeon, Beomseok
Laboratory prognostic factors for the long-term survival of multiple system atrophy
title Laboratory prognostic factors for the long-term survival of multiple system atrophy
title_full Laboratory prognostic factors for the long-term survival of multiple system atrophy
title_fullStr Laboratory prognostic factors for the long-term survival of multiple system atrophy
title_full_unstemmed Laboratory prognostic factors for the long-term survival of multiple system atrophy
title_short Laboratory prognostic factors for the long-term survival of multiple system atrophy
title_sort laboratory prognostic factors for the long-term survival of multiple system atrophy
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613998/
https://www.ncbi.nlm.nih.gov/pubmed/36302764
http://dx.doi.org/10.1038/s41531-022-00413-9
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