Cargando…

Prognostic role of HPV integration status and molecular profile in advanced anal carcinoma: An ancillary study to the epitopes-HPV02 trial

Squamous Cell Carcinoma of the Anal canal (SCCA) is a rare disease associated with a Human Papillomavirus (HPV) infection in most cases, predominantly the HPV16 genotype. About 15% of SCCA are diagnosed in metastatic stage and some will relapse after initial chemoradiotherapy (CRT). Treatment of pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Debernardi, Alice, Meurisse, Aurélia, Prétet, Jean-Luc, Guenat, David, Monnien, Franck, Spehner, Laurie, Vienot, Angélique, Roncarati, Patrick, André, Thierry, Abramowitz, Laurent, Molimard, Chloé, Mougin, Christiane, Herfs, Michael, Kim, Stefano, Borg, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614213/ https://www.ncbi.nlm.nih.gov/pubmed/36313663 http://dx.doi.org/10.3389/fonc.2022.941676

Ejemplares similares

Anti-Telomerase CD4(+) Th1 Immunity and Monocytic-Myeloid-Derived-Suppressor Cells Are Associated with Long-Term Efficacy Achieved by Docetaxel, Cisplatin, and 5-Fluorouracil (DCF) in Advanced Anal Squamous Cell Carcinoma: Translational Study of Epitopes-HPV01 and 02 Trials
por: Spehner, Laurie, et al.
Publicado: (2020)

Pooled analysis of 115 patients from updated data of Epitopes-HPV01 and Epitopes-HPV02 studies in first-line advanced anal squamous cell carcinoma
por: Kim, Stefano, et al.
Publicado: (2020)

Exosomes and Other Extracellular Vesicles in HPV Transmission and Carcinogenesis
por: Guenat, David, et al.
Publicado: (2017)

New HPV16 viral biomarkers to understand the progression of cervical lesions towards cancer
por: Prétet, Jean-Luc, et al.
Publicado: (2014)

Present and Future Research on Anal Squamous Cell Carcinoma
por: Spehner, Laurie, et al.
Publicado: (2021)

HPV16 Load Is a Potential Biomarker to Predict Risk of High-Grade Cervical Lesions in High-Risk HPV-Infected Women: A Large Longitudinal French Hospital-Based Cohort Study
por: Baumann, Antoine, et al.
Publicado: (2021)

5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression
por: Morel, Adrien, et al.
Publicado: (2017)

Development and interlaboratory agreement of real-time PCR for HPV16 quantification in liquid-based cervical samples
por: Guenat, David, et al.
Publicado: (2018)

Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism
por: Paget-Bailly, Philippe, et al.
Publicado: (2019)

A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine
por: Herfs, Michael, et al.
Publicado: (2018)

High HPV prevalence and need for ancillary care
por: Brown, Brandon
Publicado: (2014)

A Phase II Study Evaluating the Interest to Combine UCPVax, a Telomerase CD4 T(H)1-Inducer Cancer Vaccine, and Atezolizumab for the Treatment of HPV Positive Cancers: VolATIL Study
por: Rebucci-Peixoto, Magali, et al.
Publicado: (2022)

Apoptotic HPV Positive Cancer Cells Exhibit Transforming Properties
por: Gaiffe, Emilie, et al.
Publicado: (2012)

Effect of Infliximab on the UVB-Induced Apoptosis of Keratinocytes Infected by HPV38 E6/E7
por: Aubin, François, et al.
Publicado: (2013)

Human papillomavirus DNA and p16 expression in head and neck squamous cell carcinoma in young French patients
por: Molimard, Chloé, et al.
Publicado: (2021)

Persistence of anal squamous intraepithelial lesions and anal HPV infection in HIV-infected patientsdespite immune restoration under cART
por: Piketty, C, et al.
Publicado: (2010)

Validation of Novaprep(®) HQ+ liquid-based cytology medium for high-risk human papillomavirus detection by hc2
por: Guenat, David, et al.
Publicado: (2016)

Cervical, anal and oral HPV detection and HPV type concordance among women referred for colposcopy
por: Nasioutziki, Maria, et al.
Publicado: (2020)

HPV status and HPV16 viral load in anal cancer and its association with clinical outcome
por: Guerendiain, Daniel, et al.
Publicado: (2022)

Potential impact of a nonavalent HPV vaccine on the occurrence of HPV-related diseases in France
por: Riethmuller, Didier, et al.
Publicado: (2015)

ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
por: Hidalgo-Tenorio, Carmen, et al.
Publicado: (2019)

CD8(+) CD226(high) T cells in liver metastases dictate the prognosis of colorectal cancer patients treated with chemotherapy and radical surgery
por: Viot, Julien, et al.
Publicado: (2023)

HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues
por: Stanley, Margaret A, et al.
Publicado: (2012)

SALL4‐related gene signature defines a specific stromal subset of pancreatic ductal adenocarcinoma with poor prognostic features
por: Vienot, Angélique, et al.
Publicado: (2023)

The exon junction complex core factor eIF4A3 is a key regulator of HPV16 gene expression
por: Meznad, Koceila, et al.
Publicado: (2021)

Anal High-risk HPV and Liquid-based Cytology of Immunocompetent Brazilian Women with Genital High-risk HPV
por: Melo, Karla Maria Rêgo Leopoldo, et al.
Publicado: (2022)

Cervical and anal HPV infection and dysplasia in HIV-infected women
por: Stier, EA, et al.
Publicado: (2009)

Significance of HPV16 Viral Load Testing in Anal Cancer
por: Małusecka, Ewa, et al.
Publicado: (2020)

Prevention and control of HPV and HPV-related cancers in France: the evolving landscape and the way forward – a meeting report
por: Waheed, Dur-e-Nayab, et al.
Publicado: (2023)

Comparative Performance of Anyplex II HPV28 and Cobas 4800 Human Papillomavirus (HPV) Assays for High-Risk HPV Detection in Self-collected Anal Samples
por: Delvallez, Gauthier, et al.
Publicado: (2023)

Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study)
por: Kim, Stefano, et al.
Publicado: (2017)

Anal HIV DNA is associated with high-risk HPV genotypes in anal cytology specimens obtained for anal neoplasia screening
por: Shiramizu, Bruce, et al.
Publicado: (2012)

HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection
por: Beachler, Daniel C., et al.
Publicado: (2016)

The Clinical Utility of Circulating HPV DNA Biomarker in Oropharyngeal, Cervical, Anal, and Skin HPV-Related Cancers: A Review
por: Andrioaie, Ioana Maria, et al.
Publicado: (2023)

DCF versus doublet chemotherapy as first-line treatment of advanced squamous anal cell carcinoma: a multicenter propensity score-matching study
por: Kim, Stefano, et al.
Publicado: (2023)

Anal Neoplasia in Inflammatory Bowel Disease Is Associated With HPV and Perianal Disease
por: Ruel, Joannie, et al.
Publicado: (2016)

Seroconversion following anal and genital HPV infection in men: The HIM study
por: Giuliano, Anna R., et al.
Publicado: (2015)

HPV vaccination to prevent recurrence of anal intraepithelial neoplasia in HIV+ MSM
por: Gosens, Karien C.M., et al.
Publicado: (2021)

Awareness of cervical cancer among women attending an HIV treatment centre: a cross-sectional study from Morocco
por: Belglaiaa, Essaada, et al.
Publicado: (2018)

HPV-Induced Anal and Peri-Anal Neoplasia, a Surgeon’s Experience: 5-Year Case Series
por: Kosmidis, Christoforos, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n1ds6bdbjsva7brm77a346tobt