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Health disparities in outcomes of pediatric systemic lupus erythematosus

Healthcare disparities exist throughout the United States, and disparities in healthcare delivery are responsible for a substantial portion of preventable morbidity and mortality. SLE disproportionately affects racial and ethnic minoritized groups, including Blacks, Hispanics, and Asians/Pacific Isl...

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Autores principales: Vara, Emily, Gilbert, Mileka, Ruth, Natasha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614219/
https://www.ncbi.nlm.nih.gov/pubmed/36313870
http://dx.doi.org/10.3389/fped.2022.879208
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author Vara, Emily
Gilbert, Mileka
Ruth, Natasha M.
author_facet Vara, Emily
Gilbert, Mileka
Ruth, Natasha M.
author_sort Vara, Emily
collection PubMed
description Healthcare disparities exist throughout the United States, and disparities in healthcare delivery are responsible for a substantial portion of preventable morbidity and mortality. SLE disproportionately affects racial and ethnic minoritized groups, including Blacks, Hispanics, and Asians/Pacific Islanders. Specifically, Black females have a 3 to 4-fold increased risk of developing SLE than White females. Population studies funded through the Centers for Disease Control have examined variations in disease outcomes among the different populations around the United States. For example, studies have shown that lupus nephritis, anti-phospholipid syndrome, and thrombocytopenia are more likely to affect racial and ethnic minorities than Whites. In addition, the Center for Disease Control WONDER (Wide-ranging Online Data for Epidemiologic Research) database found SLE was the seventh leading cause of death for all women aged 15–25 years and the fifth leading cause of death for African American and Hispanic females. From these studies, we know SLE primarily affects racial and ethnic minorities, but we do not know why these groups are at increased risk of developing the disease or have worse outcomes. By examining the underlying mechanisms of health disparities within our patient populations and mitigation strategies, we will further understand and provide better treatment for our patients. This review will discuss current research related to health disparities and health outcomes in childhood-onset SLE (cSLE).
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spelling pubmed-96142192022-10-29 Health disparities in outcomes of pediatric systemic lupus erythematosus Vara, Emily Gilbert, Mileka Ruth, Natasha M. Front Pediatr Pediatrics Healthcare disparities exist throughout the United States, and disparities in healthcare delivery are responsible for a substantial portion of preventable morbidity and mortality. SLE disproportionately affects racial and ethnic minoritized groups, including Blacks, Hispanics, and Asians/Pacific Islanders. Specifically, Black females have a 3 to 4-fold increased risk of developing SLE than White females. Population studies funded through the Centers for Disease Control have examined variations in disease outcomes among the different populations around the United States. For example, studies have shown that lupus nephritis, anti-phospholipid syndrome, and thrombocytopenia are more likely to affect racial and ethnic minorities than Whites. In addition, the Center for Disease Control WONDER (Wide-ranging Online Data for Epidemiologic Research) database found SLE was the seventh leading cause of death for all women aged 15–25 years and the fifth leading cause of death for African American and Hispanic females. From these studies, we know SLE primarily affects racial and ethnic minorities, but we do not know why these groups are at increased risk of developing the disease or have worse outcomes. By examining the underlying mechanisms of health disparities within our patient populations and mitigation strategies, we will further understand and provide better treatment for our patients. This review will discuss current research related to health disparities and health outcomes in childhood-onset SLE (cSLE). Frontiers Media S.A. 2022-10-14 /pmc/articles/PMC9614219/ /pubmed/36313870 http://dx.doi.org/10.3389/fped.2022.879208 Text en Copyright © 2022 Vara, Gilbert and Ruth. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Vara, Emily
Gilbert, Mileka
Ruth, Natasha M.
Health disparities in outcomes of pediatric systemic lupus erythematosus
title Health disparities in outcomes of pediatric systemic lupus erythematosus
title_full Health disparities in outcomes of pediatric systemic lupus erythematosus
title_fullStr Health disparities in outcomes of pediatric systemic lupus erythematosus
title_full_unstemmed Health disparities in outcomes of pediatric systemic lupus erythematosus
title_short Health disparities in outcomes of pediatric systemic lupus erythematosus
title_sort health disparities in outcomes of pediatric systemic lupus erythematosus
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614219/
https://www.ncbi.nlm.nih.gov/pubmed/36313870
http://dx.doi.org/10.3389/fped.2022.879208
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