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Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature

Solitary fibrous tumor (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was initially discovered in the mediastinal pleura and then described in many extra-pleural sites. The reports of primary solitary fibrous tumor of bone are extremely rare and only a few cases have been previously ment...

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Autores principales: Coppola, Giulia, Zoccali, Carmine, Baldi, Jacopo, Annovazzi, Alessio, Daralioti, Thedora, Vescovo, Mariavittoria, Covello, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614297/
https://www.ncbi.nlm.nih.gov/pubmed/36305024
http://dx.doi.org/10.32074/1591-951X-524
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author Coppola, Giulia
Zoccali, Carmine
Baldi, Jacopo
Annovazzi, Alessio
Daralioti, Thedora
Vescovo, Mariavittoria
Covello, Renato
author_facet Coppola, Giulia
Zoccali, Carmine
Baldi, Jacopo
Annovazzi, Alessio
Daralioti, Thedora
Vescovo, Mariavittoria
Covello, Renato
author_sort Coppola, Giulia
collection PubMed
description Solitary fibrous tumor (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was initially discovered in the mediastinal pleura and then described in many extra-pleural sites. The reports of primary solitary fibrous tumor of bone are extremely rare and only a few cases have been previously mentioned in the literature, most of which in flat and short bones. Here we present the case of a 53-year-old female, who was referred to the emergency department of a peripheral hospital after an accidental fall. Imaging studies revealed an intertrochanteric fracture with an underlying intramedullary lytic lesion. A biopsy was performed and a diagnosis of Ewing sarcoma was initially suggested. She arrived at our hospital where we reevaluated the case. The biopsy was reviewed and a diagnosis of intraosseous SFT was proposed. She underwent en-block resection of the proximal right femur. Primary SFTs of the bone are, like in our case, easily misdiagnosed due to the low specificity of the imaging studies and the extreme rarity of the localization. An accurate diagnosis and early resection are very important and with careful long-term follow-up is essential, particularly in those who with malignant behavior, for the early detection of possible recurrence or metastasis.
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spelling pubmed-96142972022-11-03 Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature Coppola, Giulia Zoccali, Carmine Baldi, Jacopo Annovazzi, Alessio Daralioti, Thedora Vescovo, Mariavittoria Covello, Renato Pathologica Case Report Solitary fibrous tumor (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was initially discovered in the mediastinal pleura and then described in many extra-pleural sites. The reports of primary solitary fibrous tumor of bone are extremely rare and only a few cases have been previously mentioned in the literature, most of which in flat and short bones. Here we present the case of a 53-year-old female, who was referred to the emergency department of a peripheral hospital after an accidental fall. Imaging studies revealed an intertrochanteric fracture with an underlying intramedullary lytic lesion. A biopsy was performed and a diagnosis of Ewing sarcoma was initially suggested. She arrived at our hospital where we reevaluated the case. The biopsy was reviewed and a diagnosis of intraosseous SFT was proposed. She underwent en-block resection of the proximal right femur. Primary SFTs of the bone are, like in our case, easily misdiagnosed due to the low specificity of the imaging studies and the extreme rarity of the localization. An accurate diagnosis and early resection are very important and with careful long-term follow-up is essential, particularly in those who with malignant behavior, for the early detection of possible recurrence or metastasis. Pacini Editore srl 2022-10-01 /pmc/articles/PMC9614297/ /pubmed/36305024 http://dx.doi.org/10.32074/1591-951X-524 Text en © 2022 Copyright by Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access journal distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license: the work can be used by mentioning the author and the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Case Report
Coppola, Giulia
Zoccali, Carmine
Baldi, Jacopo
Annovazzi, Alessio
Daralioti, Thedora
Vescovo, Mariavittoria
Covello, Renato
Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title_full Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title_fullStr Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title_full_unstemmed Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title_short Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
title_sort primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614297/
https://www.ncbi.nlm.nih.gov/pubmed/36305024
http://dx.doi.org/10.32074/1591-951X-524
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