Pharyngeal pathology in a mouse model of oculopharyngeal muscular dystrophy is associated with impaired basal autophagy in myoblasts

Oculopharyngeal muscular dystrophy (OPMD) is a late-onset dominant disease that primarily affects craniofacial muscles. Despite the fact that the genetic cause of OPMD is known to be expansion mutations in the gene encoding the nuclear polyadenosine RNA binding protein PABPN1, the molecular mechanis...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zeuthen, Christopher, Zhu, Carol, Wu, Fang, Mezzell, Allison T., Whitlow, Thomas J., Choo, Hyojung J., Vest, Katherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614327/
https://www.ncbi.nlm.nih.gov/pubmed/36313551
http://dx.doi.org/10.3389/fcell.2022.986930

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