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Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc

The homeobox transcription factors HoxA9 and Meis1 are causally involved in the etiology of acute myeloid leukemia. While HoxA9 alone immortalizes cells, cooperation with Meis1 is necessary to induce a full leukemic phenotype. Here, we applied degron techniques to elucidate the leukemogenic contribu...

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Detalles Bibliográficos
Autores principales:	Garcia-Cuellar, Maria-Paz, Prinz, Andreas, Slany, Robert K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2022
Materias:	Article - Acute Myeloid Leukemia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614532/ https://www.ncbi.nlm.nih.gov/pubmed/35546301 http://dx.doi.org/10.3324/haematol.2022.280831

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