circEXOC5 promotes acute lung injury through the PTBP1/Skp2/Runx2 axis to activate autophagy

To understand the pathogenesis of acute lung injury (ALI), we focused on circEXOC5, a significantly up-regulated circular RNA in ALI. Using the in vivo cecal ligation and puncture (CLP)–induced ALI mouse model and in vitro LPS-challenged mouse pulmonary microvascular endothelial cell (MPVEC) model,...

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Detalles Bibliográficos
Autores principales: Gao, Pei, Wu, Beirong, Ding, Ying, Yin, Bingru, Gu, Haoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614700/
https://www.ncbi.nlm.nih.gov/pubmed/36302650
http://dx.doi.org/10.26508/lsa.202201468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614700/
https://www.ncbi.nlm.nih.gov/pubmed/36302650
http://dx.doi.org/10.26508/lsa.202201468

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