A Cantú syndrome mutation produces dual effects on K(ATP) channels by disrupting ankyrin B regulation

ATP-sensitive potassium (K(ATP)) channels composed of Kir6.x and sulfonylurea receptor (SURs) subunits couple cellular metabolism to electrical activity. Cantú syndrome (CS) is a rare disease caused by mutations in the genes encoding Kir6.1 (KCNJ8) and SUR2A (ABCC9) that produce K(ATP) channel hyper...

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Detalles Bibliográficos
Autores principales: Crespo-García, Teresa, Rubio-Alarcón, Marcos, Cámara-Checa, Anabel, Dago, María, Rapún, Josu, Nieto-Marín, Paloma, Marín, María, Cebrián, Jorge, Tamargo, Juan, Delpón, Eva, Caballero, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614705/
https://www.ncbi.nlm.nih.gov/pubmed/36287534
http://dx.doi.org/10.1085/jgp.202112995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614705/
https://www.ncbi.nlm.nih.gov/pubmed/36287534
http://dx.doi.org/10.1085/jgp.202112995

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