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A Cantú syndrome mutation produces dual effects on K(ATP) channels by disrupting ankyrin B regulation
ATP-sensitive potassium (K(ATP)) channels composed of Kir6.x and sulfonylurea receptor (SURs) subunits couple cellular metabolism to electrical activity. Cantú syndrome (CS) is a rare disease caused by mutations in the genes encoding Kir6.1 (KCNJ8) and SUR2A (ABCC9) that produce K(ATP) channel hyper...
Autores principales: | Crespo-García, Teresa, Rubio-Alarcón, Marcos, Cámara-Checa, Anabel, Dago, María, Rapún, Josu, Nieto-Marín, Paloma, Marín, María, Cebrián, Jorge, Tamargo, Juan, Delpón, Eva, Caballero, Ricardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614705/ https://www.ncbi.nlm.nih.gov/pubmed/36287534 http://dx.doi.org/10.1085/jgp.202112995 |
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