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An improved U-net based retinal vessel image segmentation method
Diabetic retinopathy is not just the most common complication of diabetes but also the leading cause of adult blindness. Currently, doctors determine the cause of diabetic retinopathy primarily by diagnosing fundus images. Large-scale manual screening is difficult to achieve for retinal health scree...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614856/ https://www.ncbi.nlm.nih.gov/pubmed/36311363 http://dx.doi.org/10.1016/j.heliyon.2022.e11187 |
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author | Ren, Kan Chang, Longdan Wan, Minjie Gu, Guohua Chen, Qian |
author_facet | Ren, Kan Chang, Longdan Wan, Minjie Gu, Guohua Chen, Qian |
author_sort | Ren, Kan |
collection | PubMed |
description | Diabetic retinopathy is not just the most common complication of diabetes but also the leading cause of adult blindness. Currently, doctors determine the cause of diabetic retinopathy primarily by diagnosing fundus images. Large-scale manual screening is difficult to achieve for retinal health screen. In this paper, we proposed an improved U-net network for segmenting retinal vessels. Firstly, due to the lack of retinal data, pre-processing of the raw data is required. The data processed by grayscale transformation, normalization, CLAHE, gamma transformation. Data augmentation can prevent overfitting in the training process. Secondly, the basic network structure model U-net is built, and the Bi-FPN network is fused based on U-net. Datasets from a public challenge are used to evaluate the performance of the proposed method, which is able to detect vessel SP of 0.8604, SE of 0.9767, ACC of 0.9651, and AUC of 0.9787. |
format | Online Article Text |
id | pubmed-9614856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-96148562022-10-29 An improved U-net based retinal vessel image segmentation method Ren, Kan Chang, Longdan Wan, Minjie Gu, Guohua Chen, Qian Heliyon Research Article Diabetic retinopathy is not just the most common complication of diabetes but also the leading cause of adult blindness. Currently, doctors determine the cause of diabetic retinopathy primarily by diagnosing fundus images. Large-scale manual screening is difficult to achieve for retinal health screen. In this paper, we proposed an improved U-net network for segmenting retinal vessels. Firstly, due to the lack of retinal data, pre-processing of the raw data is required. The data processed by grayscale transformation, normalization, CLAHE, gamma transformation. Data augmentation can prevent overfitting in the training process. Secondly, the basic network structure model U-net is built, and the Bi-FPN network is fused based on U-net. Datasets from a public challenge are used to evaluate the performance of the proposed method, which is able to detect vessel SP of 0.8604, SE of 0.9767, ACC of 0.9651, and AUC of 0.9787. Elsevier 2022-10-21 /pmc/articles/PMC9614856/ /pubmed/36311363 http://dx.doi.org/10.1016/j.heliyon.2022.e11187 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Ren, Kan Chang, Longdan Wan, Minjie Gu, Guohua Chen, Qian An improved U-net based retinal vessel image segmentation method |
title | An improved U-net based retinal vessel image segmentation method |
title_full | An improved U-net based retinal vessel image segmentation method |
title_fullStr | An improved U-net based retinal vessel image segmentation method |
title_full_unstemmed | An improved U-net based retinal vessel image segmentation method |
title_short | An improved U-net based retinal vessel image segmentation method |
title_sort | improved u-net based retinal vessel image segmentation method |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614856/ https://www.ncbi.nlm.nih.gov/pubmed/36311363 http://dx.doi.org/10.1016/j.heliyon.2022.e11187 |
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