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An Adaptable Physiological Model of Endocytic Megalin Trafficking in Opossum Kidney Cells and Mouse Kidney Proximal Tubule

The cells that comprise the proximal tubule (PT) are specialized for high-capacity apical endocytosis necessary to maintain a protein-free urine. Filtered proteins are reclaimed via receptor-mediated endocytosis facilitated by the multiligand receptors megalin and cubilin. Despite the importance of...

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Detalles Bibliográficos
Autores principales: Shipman, Katherine E, Long, Kimberly R, Cowan, Isabella A, Rbaibi, Youssef, Baty, Catherine J, Weisz, Ora A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614980/
https://www.ncbi.nlm.nih.gov/pubmed/36325513
http://dx.doi.org/10.1093/function/zqac046

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