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An Adaptable Physiological Model of Endocytic Megalin Trafficking in Opossum Kidney Cells and Mouse Kidney Proximal Tubule
The cells that comprise the proximal tubule (PT) are specialized for high-capacity apical endocytosis necessary to maintain a protein-free urine. Filtered proteins are reclaimed via receptor-mediated endocytosis facilitated by the multiligand receptors megalin and cubilin. Despite the importance of...
Autores principales: | Shipman, Katherine E, Long, Kimberly R, Cowan, Isabella A, Rbaibi, Youssef, Baty, Catherine J, Weisz, Ora A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9614980/ https://www.ncbi.nlm.nih.gov/pubmed/36325513 http://dx.doi.org/10.1093/function/zqac046 |
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