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Uterine Lavage Identifies Cancer Mutations and Increased TP53 Somatic Mutation Burden in Individuals with Ovarian Cancer

Current screening methods for ovarian cancer have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with TP53 ultradeep sequencing for the detection of disseminated ovarian cancer cells has emerged as a promising tool, but this approach has not been tested for early...

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Detalles Bibliográficos
Autores principales:	Ghezelayagh, Talayeh S., Kohrn, Brendan F., Fredrickson, Jeanne, Manhardt, Enna, Radke, Marc R., Katz, Ronit, Gray, Heidi J., Urban, Renata R., Pennington, Kathryn P., Liao, John B., Doll, Kemi M., Simons, Elise J., Burzawa, Jennifer K., Goff, Barbara A., Speiser, Paul, Swisher, Elizabeth M., Norquist, Barbara M., Risques, Rosa Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615025/ https://www.ncbi.nlm.nih.gov/pubmed/36311816 http://dx.doi.org/10.1158/2767-9764.CRC-22-0314

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