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Development of an Effective Monoclonal Antibody against Heroin and Its Metabolites Reveals Therapies Have Mistargeted 6-Monoacetylmorphine and Morphine over Heroin

[Image: see text] The opioid epidemic is a global public health crisis that has failed to abate with current pharmaceutical treatments. Moreover, these FDA-approved drugs possess numerous problems such as adverse side effects, short half-lives, abuse potential, and recidivism after discontinued use....

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Detalles Bibliográficos
Autores principales: Lee, Jinny Claire, Eubanks, Lisa M., Zhou, Bin, Janda, Kim D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615117/
https://www.ncbi.nlm.nih.gov/pubmed/36313156
http://dx.doi.org/10.1021/acscentsci.2c00977