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Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide
BACKGROUND: Although protein-based methods using cell-penetrating peptides such as TAT have been expected to provide an alternative approach to siRNA delivery, the low efficiency of endosomal escape of siRNA/protein complexes taken up into cells by endocytosis remains a problem. Here, to overcome th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615171/ https://www.ncbi.nlm.nih.gov/pubmed/36303212 http://dx.doi.org/10.1186/s12951-022-01667-4 |