Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide

BACKGROUND: Although protein-based methods using cell-penetrating peptides such as TAT have been expected to provide an alternative approach to siRNA delivery, the low efficiency of endosomal escape of siRNA/protein complexes taken up into cells by endocytosis remains a problem. Here, to overcome th...

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Detalles Bibliográficos
Autores principales: Nakamura, Momoko, Fujiwara, Kei, Doi, Nobuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615171/
https://www.ncbi.nlm.nih.gov/pubmed/36303212
http://dx.doi.org/10.1186/s12951-022-01667-4

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